Full Dose TPA for High Risk PE with Cardiac Arrest

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50-mg IV over 15 minutes

50mg IV over 2 hours

No bolus

PTT every 2 hours

Start Heparin once PTT is less than 1.5 X normal

20mg IV over 15 minutes

80mg IV over 2 hours

No bolus

PTT every 2 hours

Start Heparin once PTT is less than 1.5 X normal

10-20mg IV over 15 minutes

30-40mg IV over 2 hours

No bolus

PTT every 2 hours

Start Heparin once PTT is less than 1.5 X normal